Cytokine patterns after therapy with Avonex®, Rebif®, Betaferon®and CinnoVex™ in relapsing–remitting multiple sclerosis in Iranian patients

Cytokine patterns after therapy with Avonex®, Rebif®, Betaferon® and CinnoVex™ in relapsing-remitting multiple sclerosis in Iranian patients.

AIM Several lines of evidence exist which suggest that changes in the expression of circulating cytokines are linked to the development or reoccurrence of multiple sclerosis (MS). This study aimed to evaluate the serum levels of relevant cytokines after therapy with IFN-β formulations in MS patients. MATERIALS & METHODS In this study, blood samples were collected from 70 MS patients undergoin...

cytokine patterns after therapy with avonex®, rebif®, betaferon® and cinnovex® in relapsing–remitting multiple sclerosis in iranian patients

Group Quality of Life Therapy in Patients with Multiple Sclerosis

Objective: Multiple sclerosis (MS) has several physical, psychological, and psychiatric symptoms. Regarding the psychological impact of MS on aspects of life, this study sought to examine the effect of group quality of life therapy on depression and anxiety in these patients. Methods: Two groups of 15 matched patients with MS were randomly assigned to experimental and control groups after co...

Th1, Th2 and Th17 Cytokine Profile in Patients with Multiple Sclerosis Following Treatment with Rapamycin

Background: Management of multiple sclerosis (MS) is based on the usage of immunosuppressive and immune-modulating medications. Cytokines play an important role in the pathogenesis of MS. Objective: To evaluate the effects of rapamycin on the concentrations of Th1/Th2/Th17 serum cytokines in patients with MS. Methods: Six patients with relapsing remitting MS as a case group and 6 healthy indivi...

Seizure in Iranian patients with multiple sclerosis

BACKGROUND There is a broad variation in reported frequencies of seizure in multiple sclerosis (MS). In this study, the seizure and its characteristics analyzed among a large group of patients with MS. PATIENTS AND METHODS We reviewed the medical records of all definite MS patients referred to the MS Clinic of Kashani hospital, Isfahan, Iran, between 2007 and 2011. RESULTS Altogether, 34 ca...